Table 1.
Clinical Characteristics in Cases of Posterior Reversible Encephalopathy Syndrome, Stratified by Steroid Exposure
| Characteristica | No Steroids (N=55) | Current Steroids (N=44) | P |
|---|---|---|---|
| Age, mean (SD), y | 50.4 (21.6) | 45.1 (22.0) | 0.23 |
| Female | 43 (78%) | 31 (71%) | 0.38 |
| Hypertension | 24 (44%) | 11 (32%) | 0.79 |
| Chronic kidney disease | 12 (22%) | 6 (14%) | 0.29 |
| Active cancer | 27 (49%) | 32 (73%) | 0.02 |
| Active chemotherapyb | 25 (46%) | 33 (75%) | <0.01 |
| Autoimmune disease | 4 (7%) | 10 (23%) | 0.04 |
| Active immunosuppressionb | 3 (6%) | 18 (41%) | <0.01 |
| History of brain radiation | 2 (4%) | (16%) | 0.07 |
| Status post bone marrow transplantation | 3 (6%) | 16 (36%) | <0.01 |
| Peripartum | 8 (15%) | 0 (0) | 0.01 |
| Active sepsis | 11 (20%) | 16 (36%) | 0.11 |
| Peak systolic blood pressure, mean (SD), mm Hg | 184.5 (35.1) | 174.5 (27.0) | 0.12 |
| Serum creatinine, mean (SD), mg/dL | 1.7 (2.0) | 1.6 (2.0) | 0.89 |
| Serum sodium, mean (SD), mmol/L | 138.1 (4.4) | 137.7 (4.2) | 0.65 |
| Serum albuminc, mean (SD), g/dL | 3.1 (0.8) | 2.8 (0.7) | 0.15 |
Abbreviations: SD, standard deviation; mm Hg, millimeters mercury; mg/dL; milligrams per deciliter; mmol/L, millimoles per liter; g/dL, grams per deciliter.
a
Data are presented as number (%) unless otherwise specified.
b
Current or within the last 30 days.
c
These data were only available for 81 patients.