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. 2017 Oct 31;12(10):e0186668. doi: 10.1371/journal.pone.0186668

Table 3. Association of melanosis coli with number of colorectal polyps of various sizesa.

Groups Numbers of colorectal polyp in different sizes (mean ± SD)
Total number Diameter ≤ 5 mm Diameter 69 mm Diameter ≥10 mm Diameter ≥20 mm
Melanosis coli (n = 203) 1.05 ± 2.05 0.74 ± 1.66 0.27 ± 1.04 0.02 ± 0.15 0.03 ± 0.16
Control (n = 436) 0.54 ± 0.96 0.35 ± 0.84 0.13 ± 0.36 0.04 ± 0.20 0.02 ± 0.16
p value 0.001* 0.002* 0.06 0.38 0.60
Degrees of melanosis coli:
Grade I (n = 128) 0.98 ±1.90 0.73 ± 1.78 0.22 ± 0.72 0.03 ± 0.17 0.02 ± 0.15
Grade II (n = 52) 1.04 ± 2.05 0.73 ± 1.39 0.23 ± 1.02 0.02 ± 0.14 0.05 ± 0.23
Grade III (n = 23) 1.46 ± 2.78 0.79 ± 1.59 0.63 ± 2.06 0 0
p value 0.58 0.98 0.14 0.63 0.30
Distribution of melanosis coli:
Right colon (n = 53) 1.13 ±2.65 0.83± 2.29 0.25 ± 1.02 0.02 ± 0.13 0.02 ± 0.13
Left colon (n = 35) 1.14 ± 1.80 0.69 ± 1.53 0.14 ± 0.42 0.03 ± 0.16 0.08 ± 0.27
Total colon (n = 115) 0.98 ± 1.82 0.71 ± 1.34 0.32 ± 1.17 0.02 ± 0.15 0.02 ± 0.13
p value 0.87 0.89 0.98 0.25 0.10

a: Patients with numerous polyps (≥20) were excluded in this comparison.

*p<0.05