Table 5. Multivariate analysis of risk factors for development of colonic polyps.
Multivariate Analysis | ||||
---|---|---|---|---|
Variables | Inflammatory or hyperplastic polyp | Low grade adenoma | Advanced adenoma or adenocarcinoma | Numerous polyps (number ≥ 20) |
OR (95% CI) | OR (95% CI) | OR (95% CI) | OR (95% CI) | |
Current smoking | 1.12 (0.22, 5.78) | 3.10 (0.88, 10.9) | 2.52 (0.36, 17.90) | 4.49 (0.66, 30.34) |
Alcohol consumption | 0.32 (0.04, 2.75) | 0.42 (0.10, 1.90) | 1.96 (0.28, 13.75) | 0.89 (0.07, 10.8) |
Family CRC history | 0.31 (0.07, 1.34) | 2.06 (1.00, 4.31) b | 1.10 (0.25, 4.85) | 1.46 (0.17, 12.5) |
Regular aspirin use | 1.15 (0.45, 2.95) | 0.71 (0.30, 1.73) | 0.54 (0.07, 4.14) | 1.05 (0.12, 8.91) |
Indications for colonoscopy (compared with Screening) | ||||
Surveillance | 0.77 (0.28, 2.13) | 2.53 (1.23, 5.20) c | 1.83 (0.48, 6.90) | 0 |
Change of bowel habit | 0.75 (0.40, 1.42) | 0.86 (0.51, 1.46) | 0.47 (0.13, 1.72) | 0.68 (0.19, 2.46) |
Bleeding | 1.67 (0.96, 2.88) | 1.45 (0.89, 2.37) | 1.80 (0.75, 4.30) | 0.70 (0.18, 2.72) |
Others | 0.66 (0.23, 1.14) | 0.85 90.51, 1.43) | 1.38 (0.56, 3.38) | 0.46 (0.09, 2.21) |
Melanosis coli | 1.72 (1.11, 2.70) a | 1.54 (1.06, 2.23) d | 0.87 (0.42, 1.81) | 16.2 (3.66, 71.6) e |
a, b, c, d, e: p<0.05