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. 2017 Oct 31;12(10):e0186668. doi: 10.1371/journal.pone.0186668

Table 5. Multivariate analysis of risk factors for development of colonic polyps.

Multivariate Analysis
Variables Inflammatory or hyperplastic polyp Low grade adenoma Advanced adenoma or adenocarcinoma Numerous polyps (number ≥ 20)
OR (95% CI) OR (95% CI) OR (95% CI) OR (95% CI)
Current smoking 1.12 (0.22, 5.78) 3.10 (0.88, 10.9) 2.52 (0.36, 17.90) 4.49 (0.66, 30.34)
Alcohol consumption 0.32 (0.04, 2.75) 0.42 (0.10, 1.90) 1.96 (0.28, 13.75) 0.89 (0.07, 10.8)
Family CRC history 0.31 (0.07, 1.34) 2.06 (1.00, 4.31) b 1.10 (0.25, 4.85) 1.46 (0.17, 12.5)
Regular aspirin use 1.15 (0.45, 2.95) 0.71 (0.30, 1.73) 0.54 (0.07, 4.14) 1.05 (0.12, 8.91)
Indications for colonoscopy (compared with Screening)
    Surveillance 0.77 (0.28, 2.13) 2.53 (1.23, 5.20) c 1.83 (0.48, 6.90) 0
    Change of bowel habit 0.75 (0.40, 1.42) 0.86 (0.51, 1.46) 0.47 (0.13, 1.72) 0.68 (0.19, 2.46)
    Bleeding 1.67 (0.96, 2.88) 1.45 (0.89, 2.37) 1.80 (0.75, 4.30) 0.70 (0.18, 2.72)
    Others 0.66 (0.23, 1.14) 0.85 90.51, 1.43) 1.38 (0.56, 3.38) 0.46 (0.09, 2.21)
Melanosis coli 1.72 (1.11, 2.70) a 1.54 (1.06, 2.23) d 0.87 (0.42, 1.81) 16.2 (3.66, 71.6) e

a, b, c, d, e: p<0.05