Table 3. Summary of the CRISPR Cas9 transfection and characterization experiments.
IRAK1- | IRAK4- | TLR9- | MyD88- | Akata px458-ctl | |
---|---|---|---|---|---|
Inactive TLR9 pathway (ko) | 13/23a | 4/10a | 5/10a | 6/10a | 0/12a |
EBV positive | 7/23b | 6/10b | 6/10b | 9/10b | 10/12b |
EBV positive / TLR9 ko | 0/13c | 3/4c | 3/5c | 5/6c | 0/0c |
a = number of single cell clones with an inactive TLR9 pathway over the total number of single cell clones analyzed
b = number of EBV positive single cell clones over the total number of single cell clones analyzed
c = number of EBV positive single cell clones over the number of single cell clones with an inactive TLR9 pathway.