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| Docking Method | Glide | Surflex | GOLD | Total from Individual Methods | Composite Docking (Druggable) | Composite Docking (Complete) |
|---|---|---|---|---|---|---|
| Top Compounds Tested | 25 | 25 | 25 | 75 | 80 | 80 |
| Active at 100 μM | 3 | 3 | 4 | 10 | 16 | 12 |
| Active at 50 μM | 1 | 0 | 2 | 3 | 12 | 8 |
| IC50 below 20 μM | 0 | 0 | 1 | 1 | 5 | 3 |
| IC50 below 5 μM | 0 | 0 | 0 | 0 | 2 | 0 |
