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Overexpression of Smad3 or suppression of Smad7 affected the cell proliferation and colony formation. (A) the cell viability was slightly increased in Smad3+6 Gy group and shSmad7+6 Gy group. * P < 0.05 vs. NC group; #P < 0.05 vs.Smad3 group; & P < 0.05 vs. shSmad7 group. (B) overexpression of Smad3 or suppression of Smad7 increased the cell colony formation; ** P < 0.01 vs. NC group; # P < 0.05 vs. NC+6 Gy group.
