Table 2. Characteristics associated with waitlist mortality by univariate and multivariate logistic regression analysis*.
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
| OLT recipients | Died on waitlistor removed | Odds ratio (95% CI) | p-value | Odds ratio (95% CI) | p-value | |
| Gender, N (%) | <0.0001 | <0.0001 | ||||
| Male | 15,560 (73.9) | 5,756 (66.7) | Ref. | Ref. | ||
| Female | 5,504 (26.1) | 2,878 (33.3) | 1.414 (1.34–1.49) | 1.261 (1.19–1.34) | ||
| Age, mean ± SD | 54.3 ± 7.1 | 55.2 ± 7.1 | 1.017 (1.01–1.02) | <0.0001 | 1.032 (1.03–1.03) | <0.0001 |
| Race/Ethnicity, N (%) | <0.0001 | 0.68 | ||||
| White | 14,639 (69.5) | 5,809 (67.3) | Ref. | Ref. | ||
| Black | 2,569 (12.2) | 960 (11.1) | 0.94 (0.87–1.02) | 0.941 (0.86–1.03) | ||
| Hispanic | 2,977 (14.1) | 1,493 (17.3) | 1.26 (1.18–1.35) | 0.975 (0.90–1.05) | ||
| Asian | 643 (3.1) | 265 (3.1) | 1.04 (0.90–1.20) | 1.022 (0.87–1.20) | ||
| Other | 236 (1.1) | 107 (1.2) | 1.14 (0.91–1.44) | 1.026 (0.80–1.32) | ||
| HCV related HCC, N (%) | <0.0001 | <0.0001 | ||||
| No | 13,259 (63.9) | 7,332 (84.9) | Ref. | Ref. | ||
| Yes | 7,805 (37.1) | 1,301 (15.1) | 0.30 (0.28–0.32) | 0.248 (0.23–0.27) | ||
| ABO blood type, N (%) | <0.0001 | <0.0001 | ||||
| 0 | 9,404 (44.6) | 4,302 (49.8) | Ref. | Ref. | ||
| A | 7,773 (36.9) | 3,224 (37.3) | 0.91 (0.86–0.96) | 0.92 (0.86–0.97) | ||
| AB | 1,109 (5.3) | 200 (2.3) | 0.39 (0.34–0.46) | 0.35 (0.29–0.41) | ||
| B | 2,778 (13.2) | 908 (10.5) | 0.71 (0.66–0.78) | 0.66 (0.60–0.72) | ||
| Diabetes, N (%) | <0.0001 | <0.0001 | ||||
| No | 16,219 (78.0) | 6,317 (74.3) | Ref. | Ref. | ||
| Yes | 4,563 (22.0) | 2,184 (25.7) | 1.23 (1.16–1.30) | 1.21 (1.13–1.28) | ||
| Region, N (%)** | <0.0001 | <0.0001 | ||||
| 1 | 763 (3.6) | 453 (5.3) | Ref. | Ref. | ||
| 2 | 2,737 (13.0) | 1,264 (14.6) | 0.78 (0.68–0.89) | 0.68 (0.59–0.79) | ||
| 3 | 3,631 (17.2) | 703 (8.1) | 0.33 (0.28–0.38) | 0.26 (0.22–0.30) | ||
| 4 | 2,152 (10.2) | 1,071 (12.4) | 0.84 (0.73–0.96) | 0.73 (0.63–0.85) | ||
| 5 | 3,166 (15.0) | 2,052 (23.8) | 1.09 (0.96–1.24) | 1.002 (0.87–1.15) | ||
| 6 | 810 (3.9) | 242 (2.8) | 0.50 (0.42–0.61) | 0.474 (0.39–0.58) | ||
| 7 | 1,291 (6.1) | 502 (5.8) | 0.66 (0.56–0.77) | 0.531 (0.45–0.63) | ||
| 8 | 1,344 (6.4) | 427 (5.0) | 0.54 (0.46–0.63) | 0.476 (0.40–0.56) | ||
| 9 | 1,351 (6.4) | 981 (11.4) | 1.22 (1.06–1.41) | 1.135 (0.98–1.32) | ||
| 10 | 1,710 (8.1) | 431 (5.0) | 0.43 (0.36–0.50) | 0.371 (0.32–0.44) | ||
| 11 | 2,109 (10.0) | 508 (5.9) | 0.41 (0.35–0.47) | 0.340 (0.21–0.40) | ||
* Adjusted for co-Variates as displayed in Table 1.
**States and areas in regions of OPTN: 1 Connecticut, Maine, Massachusetts, New Hampshire, Rhode Island, Vermont; 2 Delaware, District of Columbia, Maryland, New Jersey, Pennsylvania, Northern Virginia, West Virginia; 3 Alabama, Arkansas, Florida, Georgia, Louisiana, Mississippi, Puerto Rico 4 Oklahoma, Texas; 5 Arizona, California, Nevada, New Mexico, Utah; 6 Alaska, Hawaii, Idaho, Montana, Oregon, Washington; 7 Illinois, Minnesota, North Dakota, South Dakota, Wisconsin; 8 Colorado, Iowa, Kansas, Missouri, Nebraska, Wyoming; 9 New York; 10 Indiana, Michigan, Ohio; 11 Kentucky, North Carolina, South Carolina, Tennessee, Virginia.