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. Author manuscript; available in PMC: 2018 Mar 25.
Published in final edited form as: Nat Chem Biol. 2017 Sep 25;13(11):1195–1201. doi: 10.1038/nchembio.2475

Figure 3.

Figure 3

Structure of Corn protomer. (a) Schematic of the connectivity and stereochemistry of a protomer of the A protomer of Corn RNA, the DFHO binding site, and the t1 G-quartet of the B protomer. (b) The T1 G-quartet and cation MA. Black and orange dashed lines represent hydrogen bonds and inner-sphere coordination, respectively. (c) The T2 G-quartet and cation MB. (d) The mixed tetrad T3 and cation MB. (e) The mixed tetrad T4. (f) Side and tilted views of the T1-T4 nucleobases. Lower tiers deviate from planarity.