Table 1.
Characteristics of women with histories of normotensive and preeclamptic pregnancies
| Variable | Normotensive (n=40) |
Preeclampsia (n=40) |
P-value |
|---|---|---|---|
| Age at study consent | 59.7±4.5 | 59.4±4.8 | .78 |
| Age at 1st live birth | 24.3±3.4 | 24.2±3.7 | .90 |
| Anti-hypertensive medications | 5 (13%) | 23 (58%) | <.001 |
| Lipid lowering agents | 5 (13%) | 10 (25%) | .15 |
| Aspirin | 6 (15%) | 11 (28%) | .17 |
| Anti-inflammatory medications | 20 (50%) | 27 (68%) | .11 |
| Past or current hormone therapy | 17 (43%) | 17 (43%) | 1.00 |
| Tobacco Use: | .21 | ||
| . Never | 21 (53%) | 28 (70%) | |
| . Past | 15 (38%) | 8 (20%) | |
| . Current | 4 (10%) | 4 (10%) | |
| Clinical parameters | |||
| Body mass index (kg/m2) | 25.3 (23.1, 32.0) | 29.8 (25.9, 33.7) | .02 |
| Waist circumference (cm) | 85.3 (79.3, 99.6) | 98.0 (88.3, 104.0) | .009 |
| Systolic blood pressure (mm Hg) | 131.4±20.6 | 131.8±14.9 | .91 |
| Diastolic blood pressure (mm Hg) | 75.8±10.7 | 78.2±9.6 | .29 |
| Current hypertension | 8 (20%) | 24 (60%) | <.001 |
| Diabetes mellitus | 2 (5%) | 4 (10%) | .41 |
| Gestational diabetes mellitus | 2 (5%) | 2 (5%) | 1.00 |
| Hyperlipidemia | 29 (73%) | 32 (80%) | .43 |
| Blood chemistry | |||
| Total cholesterol (mg/dL) | 204.5 (182.0, 222.5) | 189.5 (168.0, 215.0) | .10 |
| LDL Cholesterol (mg/dL) | 123.0 (99.7, 136.4) | 106.1 (87.9, 124.3) | .09 |
| HDL Cholesterol (mg/dL) | 64.0 (50.5, 76.5) | 54.5 (41.0, 69.5) | .05 |
| Triglycerides (mg/dL) | 97.5 (72.0, 123.5) | 108.0 (85.0, 163.0) | .08 |
| If Fasting glucose (mg/dL) | 95.5 (91.0, 101.5) | 98.0 (91.5, 109.5) | .15 |
| Insulin (μIU/mL) | 4.6 (3.3, 6.0) | 7.1 (4.7, 14.8) | <.001 |
| HOMA Insulin resistance (HOMA-IR) | 1.1 (0.8, 1.5) | 1.8 (1.1, 4.0) | <.001 |
Continuous variables are reported as mean ± SD, median (IQR), or n (%)