Skip to main content
. 2017 Oct 31;12(10):e0187308. doi: 10.1371/journal.pone.0187308

Fig 1. Screening of NSCLC-SQCC tumors for somatic PIK3C2B mutations.

Fig 1

A Chromatograms of different PIK3C2BWT / PIK3C2BA3623G ratios to determine maximal assay sensitivity B Table with incidence and position of detected hotspot alterations E542K and E545K in PIK3CA with representative chromatograms of screened genomic regions C Structural domains of PIK3C2B with localization of reported mutations P117A, C1181F, H1208R and L1469F. Genomic regions analyzed via Sanger sequencing are highlighted in orange D Table with incidence and position of found alterations in PIK3C2B with representative chromatograms.