| C | Gene name | ID | log2 Fold Change | Adjusted p-value | D | Gene name | ID | log2 Fold Change | Adjusted p-value |
|---|---|---|---|---|---|---|---|---|---|
| lin-7 homolog A, crumbs cell polarity complex component | LIN7A | 0.823 | 4.00E-04 | vestigial like family member 1 | VGLL1 | -3.4168 | 1.38E-08 | ||
| microtubule associated tumor suppressor candidate 2 | MTUS2 | 0.7124 | 4.00E-04 | A-kinase anchoring protein 7 | AKAP7 | -2.9597 | 1.38E-08 | ||
| LY6/PLAUR domain containing 6B | LYPD6B | 2.0132 | 4.00E-04 | guanylate cyclase activator 2A | GUCA2A | -2.8986 | 1.38E-08 | ||
| Leucine Rich Single-Pass Membrane Protein 2 | C3orf45 | 1.285 | 4.00E-04 | lin-7 homolog A, crumbs cell polarity complex component | LIN7A | -2.2845 | 1.38E-08 | ||
| guanylate cyclase activator 2A | GUCA2A | 1.0463 | 4.00E-04 | gamma-aminobutyric acid type A receptor alpha5 subunit | GABRA5 | -2.0514 | 1.38E-08 | ||
| nitric oxide synthase trafficking | NOSTRIN | 1.2269 | 4.00E-04 | microtubule associated tumor suppressor candidate 2 | MTUS2 | -1.9404 | 1.38E-08 | ||
| A-kinase anchoring protein 7 | AKAP7 | 1.0568 | 4.00E-04 | calneuron 1 | CALN1 | -1.7263 | 1.38E-08 | ||
| vestigial like family member 1 | VGLL1 | 1.1566 | 4.00E-04 | coiled-coil domain containing 141 | CCDC141 | -1.5185 | 2.21E-08 | ||
| STEAP4 metalloreductase | STEAP4 | 1.6482 | 4.00E-04 | cannabinoid receptor 1 | CNR1 | -1.6342 | 5.05E-08 | ||
| SRY-box 6 | SOX6 | 0.9508 | 5.00E-04 | leucine rich repeat containing 7 | LRRC7 | -1.8733 | 6.20E-08 | ||
| dystrobrevin alpha | DTNA | 0.9268 | 5.00E-04 | solute carrier organic anion transporter family member 4C1 | SLCO4C1 | -2.5472 | 6.86E-08 | ||
| coiled-coil domain containing 141 | CCDC141 | 0.5392 | 8.00E-04 | docking protein 5 | DOK5 | -3.3269 | 8.84E-08 | ||
| calneuron 1 | CALN1 | 0.5788 | 8.00E-04 | POU class 6 homeobox 2 | POU6F2 | -3.2967 | 8.84E-08 | ||
| cell adhesion molecule 1 | CADM1 | 1.0328 | 8.00E-04 | aldehyde dehydrogenase 1 family member A2 | ALDH1A2 | -2.6025 | 8.84E-08 | ||
| gamma-aminobutyric acid type A receptor alpha5 subunit | GABRA5 | 0.6764 | 1.00E-03 | transmembrane protein 27 | TMEM27 | -2.4447 | 8.84E-08 | ||
| leucine rich repeat containing 7 | LRRC7 | 0.6799 | 1.00E-03 | STEAP4 metalloreductase | STEAP4 | -3.8134 | 1.25E-07 | ||
| solute carrier family 2 member 2 | SLC2A2 | 2.3039 | 1.00E-03 | MTUS2 antisense RNA 1 | MTUS2-AS1 | -2.0858 | 1.25E-07 | ||
| solute carrier organic anion transporter family member 4C1 | SLCO4C1 | 0.9252 | 1.10E-03 | dystrobrevin alpha | DTNA | -2.1122 | 2.52E-07 | ||
| neuropilin 1 | NRP1 | 1.1469 | 1.60E-03 | Leucine Rich Single-Pass Membrane Protein 2 | C3orf45 | -2.6853 | 3.05E-07 | ||
| cannabinoid receptor 1 | CNR1 | 0.5538 | 1.70E-03 | apolipoprotein H | APOH | -1.7932 | 8.04E-07 | ||
A. Differentially expressed genes in PanIN-3 samples compared to normal pancreatic duct
B: Genes overexpressed only in PanIN-3 samples
C: Genes overexpressed in PanINs compared to normal pancreatic duct
D: Genes underexpressed in PanIN compared to normal pancreatic duct