Table 2. Allele frequencies in cases and controls and odds ratio estimates for osteoarthritis.

Gene	rs number	Role	allele(A1/B)	Major allelic frequency		HWE P value2	OR(95%CI)	P-value
				case	control
MMP3	rs639752	Intron	C/A	0.33	0.31	0.09	1.10(0.82-1.46)	0.53
	rs650108	Intron	G/A	0.41	0.37	0.07	1.20(0.91-1.57)	0.20
	rs520540	Coding exon	A/G	0.33	0.31	0.09	1.10(0.82-1.46)	0.53
	rs646910	Intron	A/T	0.08	0.06	0.15	1.41(0.82-2.42)	0.21
	rs602128	Coding exon	A/G	0.33	0.30	0.21	1.14(0.85-1.52)	0.38
	rs679620	Coding exon	T/C	0.33	0.31	0.13	1.10(0.82-1.45)	0.57
	rs678815	Intron	G/C	0.32	0.31	0.13	1.04(0.78-1.40)	0.79
	rs522616	Promoter	C/T	0.41	0.41	0.06	1.00(0.76-1.32)	0.98
TIMP3	rs715572	Intron	A/G	0.38	0.32	0.65	1.30(0.99-1.72)	0.06
	rs8136803	Intron	T/G	0.04	0.05	1.00	0.83(0.43-1.60)	0.59
	rs9609643	Intron	A/G	0.13	0.15	0.61	0.85(0.58-1.25)	0.41
	rs11547635	Coding exon	T/C	0.33	0.37	0.07	0.84(0.63-1.11)	0.21

¹Minor allele; ²Site with HWE P ≤ 0.05 excluded. HWE: Hardy-Weinberg equilibrium.