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. 2017 Jul 31;8(48):83792–83801. doi: 10.18632/oncotarget.19698

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Copyright: © 2017 Zhu et al.

This is an open-access article distributed under the terms of the Creative Commons Attribution License 3.0 (CC BY 3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.

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(A) TUNEL staining of the heart. a: sham; b: heart treated with Rg1; c: heart treated with DDW. Bar = 100 μm. Arrows indicated apoptotic nuclei which were stained brown. (B) Oral administration of Rg1 significantly decreased apoptosis of the heart in mice treated with doxorubicin as compared to the DDW control, n = 5, ^*p < 0.01.