Table 5. Comparison of effects of different variables on OS of patients after transplantation.
Effects | Event(death)/total | p value |
---|---|---|
Patient age at transplant | ||
<15 yr | 2/49 | 0.043 |
≥15 yr | 5/28 | |
Diagnosis-to-transplant interval | ||
≤6 months | 1/38 | 0.036 |
>6 months | 6/39 | |
Patient sex | 0.249 | |
Female | 2/38 | |
Male | 5/39 | |
IST prior to referral for HSCT | ||
ATG included | 2/15 | 0.524 |
ATG excluded | 5/62 | |
Transfusion RBC before HSCT | ||
≥25U | 4/29 | 0.265 |
<25U | 3/48 | |
Infused MNC cells | ||
≤8×108/kg | 3/11 | 0.023 |
>8×108/kg | 4/66 | |
Infused CD34+ cells | 0.076 | |
≤3×106/kg | 3/14 | |
>3×106/kg | 4/63 | |
Conditioning regimen | 0.721 | |
A(Flu+Cy+ATG+Bu) | 4/42 | |
B(Flu+Cy+ATG) | 3/35 | |
Time to neutrophil engraftment | ||
≥12 days | 4/40 | 0.773 |
<12 days | 3/37 | |
Time to platelet engraftment | 0.423 | |
≥14 days | 5/44 | |
<14 days | 2/33 | |
aGVHD | 0.001 | |
No/Grades I-II | 3/69 | |
Grades III-IV | 4/8 | |
cGVHD | 0.001 | |
No/Limited | 4/72 | |
Extensive | 3/5 | |
Donor age | 0.037 | |
<45 yr | 4/65 | |
≥45 yr | 3/12 | |
D-R sex match | 0.684 | |
Match | 4/48 | |
Mismatch | 3/29 | |
D-R major blood group match | 0.468 | |
Match | 3/43 | |
Mismatch | 4/34 | |
D-R HLA mismatched | 0.508 | |
2-4 HLA loci | 2/31 | |
5 HLA loci | 5/46 |
D-R, donor-recipient.