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. 2017 Jul 31;8(48):83817–83830. doi: 10.18632/oncotarget.19745

Table 5. Comparison of effects of different variables on OS of patients after transplantation.

Effects Event(death)/total p value
Patient age at transplant
 <15 yr 2/49 0.043
 ≥15 yr 5/28
Diagnosis-to-transplant interval
 ≤6 months 1/38 0.036
 >6 months 6/39
Patient sex 0.249
 Female 2/38
 Male 5/39
IST prior to referral for HSCT
 ATG included 2/15 0.524
 ATG excluded 5/62
Transfusion RBC before HSCT
 ≥25U 4/29 0.265
 <25U 3/48
Infused MNC cells
 ≤8×108/kg 3/11 0.023
 >8×108/kg 4/66
Infused CD34+ cells 0.076
 ≤3×106/kg 3/14
 >3×106/kg 4/63
Conditioning regimen 0.721
 A(Flu+Cy+ATG+Bu) 4/42
 B(Flu+Cy+ATG) 3/35
Time to neutrophil engraftment
 ≥12 days 4/40 0.773
 <12 days 3/37
Time to platelet engraftment 0.423
 ≥14 days 5/44
 <14 days 2/33
aGVHD 0.001
 No/Grades I-II 3/69
 Grades III-IV 4/8
cGVHD 0.001
 No/Limited 4/72
 Extensive 3/5
Donor age 0.037
 <45 yr 4/65
 ≥45 yr 3/12
D-R sex match 0.684
 Match 4/48
 Mismatch 3/29
D-R major blood group match 0.468
 Match 3/43
 Mismatch 4/34
D-R HLA mismatched 0.508
 2-4 HLA loci 2/31
 5 HLA loci 5/46

D-R, donor-recipient.