Median age at diagnosis [yr](range) |
8(1-45) |
Disease, n(%) |
|
SAA or VSAA |
72(93) |
SAA&PNH |
5(7) |
IST prior to referral for HSCT, n(%) |
|
ATG included |
15(19) |
ATG excluded |
62(81) |
Transfusion RBC before HSCT, U(%) |
|
≥25U |
29(38) |
<25U |
48(62) |
Median age at transplant [yr](range) |
11(1-46) |
≤15yr, n(%) |
52(67) |
>15yr, n(%) |
25(33) |
Median disease duration before HSCT[m](range) |
7(2-182) |
Sex(female/male) |
38/39 |
Source of stem cells, n(%) |
|
BM+PB |
77(100) |
Regimen, n(%) |
|
A(Flu+Cy+ATG+Bu) |
42(54) |
B(Flu+Cy+ATG) |
35(46) |
Median MNCs, ×108/kg (range) |
10.10(6.30-33.63) |
Median CD34+, ×106/kg (range) |
4.77(1.01-17.72) |
Engraftment, n(%) |
|
Primary engraftment |
74(96) |
Secondary engraftment |
3(4) |
Median time of ANC ≥0.5 × 109/L [d](range) |
12(8-21) |
Median time to PLT ≥20 × 109/L [d](range) |
14(9-30) |
aGVHD, n(%) |
|
Grades II-IV |
20(26) |
Grade III-IV |
8(10) |
cGVHD, n(%) |
|
Limited |
14(18) |
Extensive |
5(7) |
Median follow-up time [m](range) |
20(1-66) |