B.
| Effects | Event(GF)/total | p value |
|---|---|---|
| Patient age at transplant | ||
| <15 yr | 0/49 | 0.019 |
| ≥15 yr | 3/28 | |
| Diagnosis-to-transplant interval | ||
| ≤6 months | 0/38 | 0.081 |
| >6 months | 3/39 | |
| IST prior to referral for HSCT | ||
| ATG included | 0/15 | 0.385 |
| ATG excluded | 3/62 | |
| Transfusion RBC before HSCT | ||
| ≥25U | 2/29 | 0.290 |
| <25U | 1/48 | |
| Infused MNC cells | ||
| ≤8×108/kg | 2/11 | 0.008 |
| >8×108/kg | 1/66 | |
| Infused CD34+ cells | 0.001 | |
| ≤3×106/kg | 3/14 | |
| >3×106/kg | 0/63 | |
| Conditioning regimen | 0.667 | |
| A(Flu+Cy+ATG+Bu) | 2/42 | |
| B(Flu+Cy+ATG) | 1/35 | |
| Donor age | 0.001 | |
| <45 yr | 0/65 | |
| ≥45 yr | 3/12 | |
| D-R sex match | 0.290 | |
| Match | 1/48 | |
| Mismatch | 2/29 | |
| D-R major blood group match | 0.700 | |
| Match | 2/43 | |
| Mismatch | 1/34 | |
| D-R HLA mismatched | 0.341 | |
| 2-4 HLA loci | 2/31 | |
| 5 HLA loci | 1/46 |
(A) Clinical data and outcome of three patients with GR or GF. (B) Comparison of effects of different variables on GF of patients after transplantation.
GF, graft failure; GR, graft rejection.
D-R, donor-recipient.