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. 2017 Aug 8;8(48):83872–83889. doi: 10.18632/oncotarget.20040

Figure 4. KX2-391 inhibits deposition of ECM in the injured peritoneum.

Figure 4

Peritoneal membrane was collected at 21 days after CG injury with or without administration of KX2-391(KX2) (A–D). (A) The peritoneal tissue lysates were subjected to immunoblot analysis with specific antibodies against collagen 1, fibronectin or GAPDH. Expression levels of collagen 1(B) and fibronectin (C) were quantified by densitometry and normalized with GAPDH, respectively. Data are means ± SEM. (n = 6). Bars with different letters (a–b) are significantly different from one another (P < 0.05). (D) Photomicrographs illustrate immunohistochemical staining of collagen 1 and fibronectin (yellow) in the submesothelial compact zone.