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. 2017 Aug 3;8(48):83900–83912. doi: 10.18632/oncotarget.19911

Figure 6. PD98059 attenuates migration and invasion of CAL27 cells whereas up-regulates p-mTOR.

Figure 6

(A): Representative images (left) indicated the migration of cells induced by PD98059 (2.5, 5 μM) and the vehicle for 48 h. Migration index was used to present the statistic result (right). (B): Representative images (left) and histogram of invasion analysis (right) from transwell assay indicated invasion ability of cells induced by PD98059 and the vehicle for 24 h. (C): Cell lysates from PD98059-treated cells for 1 h (left) and 24 h (right) were analyzed the levels of phosphorylated, total ERK1/2, mTOR and GAPDH using Western blot.