Figure 6. UBE2L3 contributes to NSCLC progression in vivo.

(A, D) A549 and NCI-H1299 cells stably expressing shUBE2L3 or control vector were subcutaneously transplanted into nude mice and the growth curves were shown. (B, E) The weights of tumors were presented as mean ± SD. (C, F) IHC staining demonstrated that knockdown of UBE2L3 inhibited NSCLC cell growth in vivo, as indicated by the expression of ki67. (Data were presented with mean ± SD of three independent experiments, ^**p<0.01).