Table 2. Association of cleaved caspase-3 (CC-3) and caspase-3 (C-3) expression levels with demographical characteristics and pathological outcomes in BMSCC patients.
| Variable | No. | CC-3 | C-3 | ||||
|---|---|---|---|---|---|---|---|
| Mean±SD | Median | p-Value | Mean±SD | Median | p-Value | ||
| Sex | |||||||
| Female | 4 | 0.50±1.00 | 0.00 | 0.557* | 5.50±0.58 | 5.50 | 0.185* |
| Male | 181 | 0.86±1.20 | 0.00 | 4.53±1.45 | 5.00 | ||
| Age, y | |||||||
| ≦40 | 25 | 0.44±0.82 | 0.00 | 0.338† | 4.00±1.76 | 4.00 | 0.077‡ |
| 41-50 | 58 | 0.97±1.28 | 0.00 | 4.76±1.37 | 5.00 | ||
| 51-60 | 56 | 0.91±1.21 | 0.00 | 4.75±1.25 | 5.00 | ||
| >60 | 46 | 0.85±1.23 | 0.00 | 4.35±1.51 | 5.00 | ||
| Cell differentiation | |||||||
| Well | 51 | 0.57±1.01 | 0.00 | 0.063† | 4.20±1.51 | 5.00 | 0.069† |
| Moderate | 125 | 0.99±1.27 | 0.00 | 4.74±1.33 | 5.00 | ||
| Poor | 9 | 0.44±0.88 | 0.00 | 4.00±2.12 | 5.00 | ||
| AJCC pathological stage | |||||||
| I, II | 112 | 0.67±1.03 | 0.00 | 0.029§ | 4.55±1.42 | 5.00 | 0.979* |
| III, IV | 73 | 1.12±1.37 | 0.00 | 4.55±1.49 | 5.00 | ||
| T classification | |||||||
| T1, T2 | 140 | 0.70±1.12 | 0.00 | 0.002§ | 4.53±1.45 | 5.00 | 0.706* |
| T3, T4 | 45 | 1.31±1.33 | 1.00 | 4.62±1.45 | 5.00 | ||
| N classification | |||||||
| N0 | 141 | 0.79±1.13 | 0.00 | 0.377§ | 4.50±1.43 | 5.00 | 0.356* |
| N1, N2 | 44 | 1.05±1.38 | 0.00 | 4.73±1.48 | 5.00 | ||
AJCC, American Joint Committee on Cancer.
*p values were estimated by student's T test.
†p values were estimated by Kruskal-Wallis 1-way ANOVA test.
‡p values were estimated by 1-way ANOVA test.
§p values were estimated by Mann-Whitney U test.