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. 2017 Sep 6;8(48):84276–84284. doi: 10.18632/oncotarget.20685

Figure 4. Pkm2 increased during reprogramming and was critical for iPS induction.

Figure 4

(A) Real-time PCR examining the expression of Pkm2, Idha and Pfkl in MEFs and ESCs. (B) Real-time PCR examining the expression of Pkm1, Pkm2 and their ratio at indicated time points during reprogramming. (C) Western blot showing the protein level of Pkm1 and Pkm2 at indicated time points during reprogramming. (D) Alkaline Phosphatase (AP) staining of iPSC colonies under Pkm knockdown. Data represented as mean ± SD; n = 3.