Table 1. Overview of inherited variants in 86 HCC pairs.
| Region/gene | Var no. (%) | Transitions | Transversions | del | ins | Non-syn | Syn | novel Var |
|---|---|---|---|---|---|---|---|---|
| Control region | 128 (21.66%) | 105 | 13 | 5 | 5 | 1 | ||
| *other non-coding | 9 (1.52%) | 5 | 0 | 2 | 2 | 0 | ||
| 12S rRNA | 21 (3.55%) | 19 | 1 | 0 | 1 | 1 | ||
| 16S rRNA | 24 (4.06%) | 23 | 1 | 0 | 0 | 2 | ||
| tRNAs | 31 (5.25%) | 28 | 2 | 0 | 1 | 4 | ||
| MT-ND1 | 37 (6.26%) | 35 | 2 | 0 | 0 | 12 | 25 | 1 |
| MT-ND2 | 29 (4.91%) | 26 | 3 | 0 | 0 | 11 | 18 | 0 |
| MT-ND3 | 11 (1.86%) | 11 | 0 | 0 | 0 | 4 | 7 | 0 |
| MT-ND4 | 40 (6.77%) | 38 | 2 | 0 | 0 | 9 | 31 | 0 |
| MT-ND4L | 6 (1.02%) | 5 | 1 | 0 | 0 | 3 | 3 | 0 |
| MT-ND5 | 62 (10.49%) | 60 | 2 | 0 | 0 | 23 | 39 | 2 |
| MT-ND6 | 13 (2.20%) | 13 | 0 | 0 | 0 | 3 | 10 | 0 |
| MT-CO1 | 38 (6.43%) | 36 | 2 | 0 | 0 | 8 | 30 | 1 |
| MT-CO2 | 24 (4.06%) | 24 | 0 | 0 | 0 | 4 | 20 | 0 |
| MT-CO3 | 27 (4.57%) | 26 | 1 | 0 | 0 | 6 | 21 | 0 |
| MT-CYB | 57 (9.64%) | 52 | 5 | 0 | 0 | 22 | 35 | 1 |
| MT-ATP6 | 25 (4.23%) | 25 | 0 | 0 | 0 | 11 | 14 | 0 |
| MT-ATP8 | 9 (1.52%) | 8 | 1 | 0 | 0 | 4 | 5 | 0 |
| Total | 591 | 539 | 36 | 7 | 9 | 120 | 258 | 13 |
*, regions interspersed between the coding gene and tRNAs.