Table 3. Differences in ALFF and ReHo values among PSPLC patients, non-PLC patients and healthy controls (P < 0.01, AlphaSim corrected).
Brain region | BA | Voxels | Maximal t value | MNI coordinates | |||
---|---|---|---|---|---|---|---|
X | Y | Z | |||||
PSPLC vs HC | |||||||
ALFF differences | R.Parahippocampal | 21 | 65 | 3.54 | 27 | −3 | −27 |
L/R.mPFC, R.ACC | 11,47 | 178 | 3.91 | 12 | 36 | −24 | |
R.MTG | 21 | 53 | 3.23 | 63 | −18 | −18 | |
L.Precentral | 6 | 73 | −3.58 | −42 | 6 | 42 | |
R.SFG | 10 | 65 | −3.28 | 27 | 45 | 21 | |
ReHo differences | L.ACC/R.ACC | 32,24 | 312 | 4.31 | 12 | 33 | 12 |
L.ITG | 37 | 42 | 2.85 | −48 | −48 | −21 | |
L.MTG | 21 | 69 | 3.50 | −54 | −36 | 0 | |
L.SFG/SMA | 6 | 74 | −3.34 | −15 | −9 | 78 | |
L.Precentral | 6 | 49 | −3.08 | −36 | −15 | 42 | |
R. IPL | 2,40 | 118 | −3.45 | 54 | −45 | 45 | |
non-PLC vs HC | |||||||
ALFF differences | R.MTG | 21 | 80 | 3.05 | 66 | −45 | −12 |
L.ITG | 20 | 64 | 2.89 | −54 | −12 | −30 | |
R.MFG/SMA | 6 | 72 | −2.76 | 6 | −12 | 69 | |
R.Precentral | 6 | 73 | −3.12 | 45 | −6 | 30 | |
ReHo differences | R.dlPFC | 9 | 63 | 2.90 | 33 | 9 | 30 |
L.MTG | 21 | 206 | 4.00 | −51 | −9 | −21 | |
L.Paracentral Lobule/ L.Precentral | 4,6 | 299 | −3.65 | −15 | −42 | 57 | |
R.Precentral | 3 | 59 | −3.94 | 27 | −27 | 60 | |
PSPLC vs non-PLC | |||||||
ALFF differences | L.Parahippocampal | 20 | 62 | 3.72 | −24 | −9 | −24 |
R.ACC/R.mPFC | 32 | 102 | 3.92 | 12 | 33 | −6 | |
L.CPL | 80 | −4.61 | −54 | −51 | −30 | ||
ReHo differences | R.ACC/R.mPFC | 32,25 | 128 | 4.03 | 9 | 39 | 0 |
R.ITG | 20 | 64 | 3.54 | 51 | −30 | −18 | |
L.dlPFC | 8 | 45 | 3.01 | −42 | 30 | 45 |
Note: Comparisons were performed at P < 0.01, corrected for multiple comparisons. Abbreviations: HC: healthy control; L.: left; R.: right; BA: Brodmann's area; T: statistical value of peak voxel with significant ALFF and ReHo differences between the two groups (negative values: < Controls; positive values: > Controls); MNI: Montreal Neurological Institute Coordinate System or Template; x, y, z: coordinates of primary peak locations in the MNI space.