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. 2017 Oct 31;7:14393. doi: 10.1038/s41598-017-14807-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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circRNA-miRNA-mRNA networks. (A) The circRNA-miRNA-mRNA network, which consists of 406 circRNAs (orange nodes), 249 miRNAs (blue nodes) and 305 disease genes (green); (B) The prediction of circMAN1A2 target genes related to ErbB signaling pathway. A total of 44 nodes and 72 edges were constructed.