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. 2017 Oct 31;7:14393. doi: 10.1038/s41598-017-14807-w

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© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Function annotations for target genes mediated by circMAN1A2-miRNA axes. (A) ErbB signaling pathway network containing thirty-three genes on circMAN1A2 mediated by its target miRNAs. The yellow boxes represented target genes containing only one miRNA, the orange boxes represented target genes contained multi-miRNAs; (B) GO annotation for the circMAN1A2 targeted genes of the ErbB signaling pathway. Only the most significantly enriched clusters were included.