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miR-215 inhibits HCC growth in vivo. A, the growth of tumors from SMMC7721 xenografts with miR-215 up-regulation, silenced PCAT-1 (shPCAT-1) or silenced CRKL (shCRKL). B, expression of miR-215, lncRNA PCAT-1, and CRKL in xenografts was examined. C, H&E staining and CRKL immunohistochemical analyses of representative xenografts. D, a working model summarizing relationships between TP53, miR-215, lncRNA PCAT-1, and CRKL. **, p < 0.01.
