Table 1.
SOF and/or LDV regimens evaluated in the BelloCell System against a genotype 1b HCV replicon cell line.
| [Sofosbuvir] (ng/ml)a | ||||
|---|---|---|---|---|
| [Ledipasvir] (pg/ml)a | 0 | EC25-SOF | EC50-SOF | EC95-SOF |
| EC25-LDV | EC25-LDVEC25-SOF | EC25-LDVEC50-SOF | EC25-LDVEC95-SOF | |
| EC50-LDV | EC50-LDVEC25-SOF | EC50-LDVEC50-SOF | EC50-LDVEC95-SOF | |
| EC95-LDV | EC95-LDVEC25-SOF | EC95-LDVEC50-SOF | EC95-LDVEC95-SOF | |
aConcentrations were determined using a 96-well plate drug screening assay.