Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2017 Nov 1;8:1242. doi: 10.1038/s41467-017-01356-z

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2017

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 7 — Inactivating pre-stimulus activity in PPC alters internal bias. a Schematic of inactivation experiment. Control (blue light directed away from PPC) and inactivation (the light directed to PPC) sessions alternated day-to-day (for 14–16 days). Continuous blue light was applied during the ITI in randomly selected trials (15%; light-on trials) in both control and inactivation sessions. b Choice sequence (black) and behavioral model fit (orange) in an example inactivation session. In this example, the mouse tended to alternate choice (i.e., the mouse most heavily weighted the previous choice history) in light-off trials, but this tendency was reduced in light-on trials. c The effect of PPC ITI inactivation on the model fit in seven separate inactivation sessions in a single mouse. Black, mean ± s.e.m. across sessions; gray, individual sessions. Wilcoxon signed rank test. The light-off model was built on a subset of light-off trials and its accuracy was assessed on the remaining light-off or light-on trials. d Average light-off model accuracy in light-off and light-on trials in inactivation sessions. Black, mean ± s.e.m. across mice; gray, individual mice. Wilcoxon one-sided signed rank test. e In trial inactivation sessions, blue light was applied from stimulus onset to the end of randomly selected trials (15%). Trial inactivation does not have a temporal overlap with ITI inactivation. f The same as d, but for trial inactivation in PPC. g The same as d, but for ITI inactivation in M1