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LTA and cardiolipin inhibit CATH-2-induced killing of S. aureus. CATH-2 was preincubated with various ratios of lipoteichoic acid from S. aureus (LTA-SA) (A), cardiolipin (B), and peptidoglycan from S. aureus (PG-SA) (C) for 1 h at 37°C. Then, mixtures were incubated with S. aureus for 3 h at 37°C, after which bacteria were serially diluted and spread plated on TSA plates. Viable colonies were counted after 16 h. One representative value per compound is demonstrated (n = 3).
