Table 2.

Number of reads for all observed HLA‐G splicing events in ccRCC samples

	Patient 1	Patient 3	Patient 4	Patient 5	B00E4I3	B00E4IS
#Reads at HLA‐G locus	4925	2709	1037	129	6503	5462
#Reads q30 at HLA‐G locus (mean)	4495	1552	110	67	5692	4605
Exon1 total reads	11	4	0	0	0	0
Exon2 total reads	243	30	2	0	238	221
Exon3 total reads	1594	410	13	5	1126	1376
Exon4 total reads	2364	525	50	17	2141	2104
Exon5 total reads	1957	687	67	52	4279	2892
Exon6 total reads	1113	315	6	6	2137	1493
Exon7 total reads	896	454	0	9	1002	743
Exon8 total reads	2214	1190	23	41	3245	2438
Retention of intron 1	22	4	0	0	20	6
Retention of intron 2	2	0	0	0	4	1
Retention of intron 3	102	25	2	2	19	49
Retention of intron 4	82	15	2	0	11	23
Retention of intron 5	154	27	8	0	184	95
Retention of intron 6	12	4	0	0	6	5
Retention of intron 7	74	31	0	0	21	37
Skipping of exon 4	5	1	0	0	29	13
Skipping of exon 5	0	0	0	0	3	0
Skipping of exon 6	4	2	0	0	11	9
Skipping of exon 7	32	6	0	0	81	41
Skipping of exon 4 and 5	2	3	0	0	6	6
Skipping of exon 4,5,6 and 7	0	0	0	0	0	0
Skipping of exon 4,5 and 7	0	0	0	0	0	0
Skipping of exon 5,6 and 7	0	0	0	0	0	0
Skipping of exon 6 and 7	5	2	0	0	24	5
Raw count of reads start exon2	132	15	0	0	64	106
Raw count of reads start exon3	4	0	0	0	0	4
Raw count of reads start exon4	72	30	6	0	101	96
Raw count of reads start exon5	8	2	0	0	15	6

Patients 1, 3, 4 and 5 are representative samples selected for exploring the diversity of HLA‐G isoforms. B00E4I3 and B00E4IS are the two samples with the highest HLA‐G expression within the CAGEKID (CAncer GEnome of the KIDney) (Scelo et al., 2014).