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. 2017 Oct 16;7(10):132. doi: 10.3390/brainsci7100132

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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Rapid test of social acquisition and recognition. The time spent for social investigation in each trial for 1 min by CD38^+/+ (WT) or CD38^−/− adult virgin males to a virgin male intruder at 30 min after a single i.p. injection of PBS, OT (A) Lipo-oxytocin-1 (LOT-1), Lipo-oxytocin-2 (LOT-2), or Lipo-oxytocin-3 (LOT-3) (B). The percent changes are illustrated between the 1st and 4th trials (C) and the 4th and 5th trials (D). n = 5–15 for each test. One-way ANOVA followed Bonferroni’s post hoc test revealed significance in C (F_6,49 = 2.779, p = 0.0209) and D (F_6,49 = 6.219, p = 0.0001). * p < 0.05, ** p < 0.01, compared with CD38^−/− treated with PBS.