3D	Three dimensional
5-FU	5-fluorouracil
AML	acute myeloid leukaemia
ATP	adenosine triphosphate
AurA	Aurora Kinase A
BAD	Bcl-2-associated death promoter
c/EBPβ	CCAAT/Enhancer Binding Protein Beta
CAMKK2	Ca2+/calmodulin-dependent protein kinase kinase 2
cDDP	cis-diamminedichloroplatinum(II)/cisplatin/cisplatinum
COL11A1	collagen type XI aplha1
COX2	cyclooxygenase-2
CTGF	connective tissue growth factor
EGF	epidermal growth factor
EMT	epithelial-to-mesenchymal transition
EOC	epithelial ovarian carcinoma
ERα	oestrogen receptor α
FABP5	fatty acid-binding protein 5
Foxo	forkhead box O
GAP	GTPase activating protein
GBM	glioblastoma multiforme
GPCR	G-protein-coupled receptor
HDAC	histone deacetylase
Hpo	Hippo
Hsp90	heat shock protein 90
IC50	half maximal inhibitory concentration
IGF1	insulin growth factor 1
K-RAS	Kirsten Rat Sarcoma Viral Oncogene Homolog
Lats	Large Tumor Suppressor Kinase 1
LPA	lysophosphatidic acid
LSC	leukaemia stem cells
Mats	Mob-as-tumour-suppressor
MLL-AF9	mixed lineage leukemia-ALL1- fused gene from chromosome 9 protein
MM	Multiple myeloma
MOBKL1A/1B	Mps one binder kinase activator-like 1A
mRNA	messenger ribonucleic acid
mSIN1	mammalian stress-activated protein kinase interacting protein 1
MTDH	metadherin
mTOR	mammalian/mechanistic target of rapamycin
MYC	v-myc myelocytomatosis viral oncogene homolog (avian)
NDRG1	N-Myc Downstream Regulated 1
nM	nanomolar
p21Cip1	cyclin-dependent kinase inhibitor 1
PDAC	pancreatic ductal adenocarcinoma
PDK1	3-phosphoinositide-dependent protein kinase 1
PH	pleckstrin homology
PI3K	phosphoinositide 3-kinase
PIF	PDK1-interacting fragment
PKB/Akt	protein kinase B
PKC	protein kinase C
PLCε	phospholipase Cε
PLK1	Polo-like kinase 1
PPAR β	peroxisome proliferator-activated receptor β
PRAS40	inhibitory subunit 40-kDa proline-rich
PtdIns(3,4,5)P3	phosphatidylinositol (3,4,5)-trisphosphate
PtdIns(4,5)P2	phosphatidylinositol (4,5)-bisphosphate
PTEN	phosphate and tensin homolog
RA	retinoic acid
RTK	receptor tyrosine kinase
Rheb	Ras homolog enriched in brain
S6K1	Ribosomal protein S6 kinase beta-1
Sav	Salvador
Ser	serine
sfRon	short-form Ron
SGK	Serum and glucocorticoid-induced protein kinase
Src	V-Src Avian Sarcoma (Schmidt-RuppinA-2) Viral Oncogene
SWH	Salvador/Warts/Hippo
TCRP1	tongue cancer resistance-related protein-1
TEADs	TEA domain transcription factors
Thr	threonine
TIMP1	tissue inhibitor of metalloproteinase-1
TNBC	triple negative breast cancer
TRAIL	tumour necrosis factor-α-related apoptosis-inducing ligand
TSC	tuberous sclerosis complex
TUSC4	tumour suppressor candidate 4
UPP	ubiquitin (Ub)-proteasome pathway
VEGF-A	vascular endothelial growth factor-A
VP-16	Etoposide Phosphate
Wts	Warts
YAP	Yes-associated protein 1
μΜ	micromolar