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. 2017 Oct 13;8(10):270. doi: 10.3390/genes8100270

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© 2017 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).

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(Patient dG15) Coronal (A) and sagittal (B) magnetic resonance (MR) images show complete loss of articular cartilage of the medial femoral and tibial condyles (International Cartilage Repair Society (ICRS) grade IV chondromalacia), thinning and shallow fissures of the articular cartilage in the lateral femoral and tibial condyles (ICRS grade IV chondromalacia), edge osteophytes and joint effusion. MR images with the dGEMRIC index values at four-time points (T0: baseline, T3: three months after autologous and microfragmented adipose tissue injection; T6: six months after autologous and microfragmented adipose tissue injection; T12: 12 months after autologous and microfragmented adipose tissue injection) (C1–C4). The scheme of the dGEMRIC index with different joint facets throughout the study period at T0, T3, T6 and T12 combined with visual analogue scale (VAS) ratings at T0, T3, T6, T12 (D).

(Patient dG15) Coronal (A) and sagittal (B) magnetic resonance (MR) images show complete loss of articular cartilage of the medial femoral and tibial condyles (International Cartilage Repair Society (ICRS) grade IV chondromalacia), thinning and shallow fissures of the articular cartilage in the lateral femoral and tibial condyles (ICRS grade IV chondromalacia), edge osteophytes and joint effusion. MR images with the dGEMRIC index values at four-time points (T0: baseline, T3: three months after autologous and microfragmented adipose tissue injection; T6: six months after autologous and microfragmented adipose tissue injection; T12: 12 months after autologous and microfragmented adipose tissue injection) (C1–C4). The scheme of the dGEMRIC index with different joint facets throughout the study period at T0, T3, T6 and T12 combined with visual analogue scale (VAS) ratings at T0, T3, T6, T12 (D).