Table 2.
Plasma glycan profiles of the initial measurements, first and second follow-up.
| Glycan | Initial Measurement (M0) | First Follow-up (M6) | Second Follow-up (M12) | p * (M0–M6) | p * (M0–M12) |
|---|---|---|---|---|---|
| GP1 | 0.125 ± 0.063 (0.046–0.277) | 0.138 ± 0.055 (0.083–0.258) | 0.127 ± 0.052 (0.044–0.254) | 0.417 | 0.996 |
| GP2 | 1.458 ± 0.97 (0.255–4.007) | 1.131 ± 0.632 (0.249–2.167) | 1.424 ± 0.955 (0.283–3.999) | 0.769 | 0.523 |
| GP3 | 0.113 ± 0.02 (0.09–0.151) | 0.121 ± 0.021 (0.099–0.161) | 0.12 ± 0.023 (0.085–0.162) | 0.065 | 0.142 |
| GP4 | 27.9 ± 8.246 (12.755–46.784) | 29.926 ± 7.142 (22.454–43.436) | 28.143 ± 7.034 (14.145–43.06) | 0.861 | 0.957 |
| GP5 | 0.168 ± 0.028 (0.136–0.218) | 0.167 ± 0.027 (0.139–0.21) | 0.172 ± 0.032 (0.132–0.237) | 0.793 | 0.366 |
| GP6 | 7.135 ± 1.299 (4.313–9.109) | 7.157 ± 1.683 (4.274–10.042) | 7.545 ± 1.663 (4.196–10.429) | 0.142 | 0.050 |
| GP7 | 0.728 ± 0.679 (0.137–2.773) | 0.506 ± 0.207 (0.14–0.759) | 0.709 ± 0.634 (0.203–2.717) | 0.667 | 0.575 |
| GP8 | 18.487 ± 2.753 (13.198–24.336) | 17.622 ± 2.368 (13.641–20.534) | 18.142 ± 2.626 (13.685–23.972) | 0.315 | 0.074 |
| GP9 | 9.416 ± 1.873 (7.167–14.423) | 9.299 ± 2.26 (7.039–14.446) | 9.377 ± 1.8 (6.998–14.379) | 0.611 | 0.562 |
| GP10 | 4.974 ± 0.983 (4.049–7.72) | 5.031 ± 1.159 (3.922–7.585) | 5.145 ± 0.991 (4.072–7.557) | 0.742 | 0.374 |
| GP11 | 0.657 ± 0.082 (0.476–0.756) | 0.672 ± 0.093 (0.526–0.785) | 0.695 ± 0.13 (0.47–0.977) | 0.753 | 0.169 |
| GP12 | 0.973 ± 0.773 (0.186–3.166) | 0.712 ± 0.298 (0.189–1.078) | 0.953 ± 0.732 (0.265–3.121) | 0.600 | 0.152 |
| GP13 | 0.276 ± 0.049 (0.2–0.356) | 0.251 ± 0.041 (0.189–0.31) | 0.275 ± 0.046 (0.207–0.37) | 0.034 | 0.841 |
| GP14 | 10.123 ± 3.266 (3.746–15.708) | 9.512 ± 3.073 (4.507–13.431) | 9.94 ± 2.932 (4.349–14.829) | 0.550 | 0.691 |
| GP15 | 1.506 ± 0.27 (0.999–1.974) | 1.475 ± 0.253 (1.092–1.867) | 1.517 ± 0.221 (1.158–1.875) | 0.197 | 0.786 |
| GP16 | 2.939 ± 0.592 (2.209–4.089) | 2.929 ± 0.613 (2.248–4.007) | 2.878 ± 0.547 (2.263–3.912) | 0.057 | 0.143 |
| GP17 | 0.956 ± 0.186 (0.611–1.159) | 0.904 ± 0.181 (0.664–1.186) | 0.939 ± 0.194 (0.658–1.232) | 0.198 | 0.992 |
| GP18 | 6.668 ± 1.498 (3.225–8.798) | 6.682 ± 1.786 (3.503–9.145) | 6.566 ± 1.449 (3.412–9.026) | 0.822 | 0.961 |
| GP19 | 1.675 ± 0.534 (0.487–2.582) | 1.802 ± 0.366 (1.271–2.326) | 1.682 ± 0.482 (0.481–2.416) | 0.941 | 0.755 |
| GP20 | 0.283 ± 0.066 (0.138–0.393) | 0.257 ± 0.055 (0.169–0.33) | 0.274 ± 0.06 (0.14–0.343) | 0.100 | 0.460 |
| GP21 | 0.48 ± 0.106 (0.312–0.577) | 0.477 ± 0.114 (0.286–0.647) | 0.458 ± 0.091 (0.27–0.578) | 0.886 | 0.151 |
| GP22 | 0.133 ± 0.049 (0.041–0.191) | 0.129 ± 0.037 (0.079–0.19) | 0.131 ± 0.04 (0.046–0.178) | 0.164 | 0.765 |
| GP23 | 1.278 ± 0.414 (0.48–2.001) | 1.375 ± 0.432 (0.753–2.048) | 1.243 ± 0.437 (0.489–1.996) | 0.331 | 0.903 |
| GP24 | 1.55 ± 0.542 (0.427–2.266) | 1.723 ± 0.39 (1.076–2.238) | 1.544 ± 0.521 (0.407–2.515) | 0.453 | 0.748 |
* Pair-wise testing with t-test for paired samples; GP: Glycan peak; M: months.