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. 2017 Oct 18;8(10):278. doi: 10.3390/genes8100278

Table 1.

Numbers of letters of the dinucleotide DNA alphabet CANA observed in the analyzed complexes of regulatory proteins and in nucleosome core particle (NCP). The incidences of the alphabet letter SQX were not analyzed, no Z-DNA letter ZZZ was observed.

The Main Structural Features of the CANA Letters CANA Letter Regulatory NCP
# % # %
A-form conformers AAA 802 4 20 0.4
conformers bridging A- to B-form A-B 925 4.7 133 2.9
conformers bridging B- to A-form B-A 1564 7.9 184 4
the most frequent “canonical” B-form BBB 7559 38.1 1548 33.7
less populated BI conformer 2B1 1692 8.5 204 4.4
less populated BI conformers with switched values of torsions α and γ 3B1 1346 6.8 201 4.4
conformer bridging BI- to BII-form B12 1380 6.9 475 10.3
BII conformers BB2 1005 5.1 490 10.7
various minor B conformers miB 827 4.2 565 12.3
conformers with bases in syn orientation, may occur in quadruplexes, other non-duplexes SQX 69 0.3 0 0
non-Assigned Steps NAN 2688 13.5 778 16.9
All Steps ASt 19,857 100 4598 100