Figure 2.
Commonly used platforms used in haploidentical-related transplantation.111 (A) University of Perugia: myeloablative conditioning and T cell-depletion with “megadose” CD34+ cell allografts. (B) Johns Hopkins: non-myeloablative conditioning with high-dose, post-transplantation cyclophosphamide. (C) Peking University: myeloablative conditioning and in vivo T cell modulation (GIAC protocol). Panel B was adapted from Luznik et al.44 used under the Creative Commons License. Ara-C: cytarabine; ATG: anti-thymocyte globulin; BM: bone marrow; Bu: busulfan; CSA: ciclosporin-A; Cy: cyclophosphamide; Flu: fludarabine; GCSF: granulocyte colony-stimulating factor; M-CCNU: semustine; MMF: mycophenolate mofetil; MTX: methotrexate; PBSC: peripheral-blood stem cell; TBI: total body irradiation.