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Coarse-grained MD simulations of myrArf/Brag2 on a membrane showing multiple PIP2 lipid-binding sites. Coarse-grained MD simulation of myrArf/Brag2 on a membrane containing PIP2 lipids at the start of the simulation (Left) and at the end (Right) of each simulation run. Multiple PIP2s bind to the proteins at various interaction sites at the end of the simulations. The PC lipids and the tails of the PS and PIP2 lipids are not shown for clarity.
