The body weight changes of rats during the experiment period. p < 0.05, vs. the control group, D1 represents the first day of the experiment, D34 represents the 34th day of the experiment, and so on. Abbreviations: Con, control group; M8: the mixture of eight common metals (Pb + Cd + Hg + Cu + Zn + Mn + Cr + Ni); M5: the mixture of five non-essential metals (Pb + Hg + Cd + Ni + Cr); M4A: the mixture of four non-essential metals (Pb + Hg + Cd + Ni); M4B: the mixture of three essential metals and one non-essential metal (Cu + Zn + Mn + Cr); M3: the mixture of three essential metals (Cu + Zn + Mn); Cr, chromium; Cu, copper; Zn, zinc; Mn, manganese.