Table 1.
Characteristics of the participants and distribution of the RNF213 p.R4810K variant
| Characteristics | ICASO | Controls |
|---|---|---|
| Number of the participants | 715 | 507 |
| Age (yrs) | ||
| Mean ± SD | 58.4 ± 12.9 | 37.2 ± 16.9 |
| Range | 15–89 | - |
| Female, n (%) | 253 (35.4) | 377 (74.4) |
| Conventional risk factors, n (%) | ||
| Hypertension | 429 (60.0) | - |
| Diabetes | 179 (25.0) | - |
| Hyperlipemia | 290 (40.6) | - |
| Coronary heart diseases | 79 (11.0) | - |
| Smoking | 277 (38.7) | - |
| Drinking | 150 (21.0) | - |
| RNF213 p.R4810K genotype | ||
| Wild type: GG (%) | 709 (99.16) | 505 (99.61) |
| Heterozygous: GA (%) | 6 (0.84) | 2 (0.39) |
| Homozygous: AA (%) | 0 (0) | 0 (0) |
| OR (95% confidence interval) | 2.14 (0.43–10.63) | |
| p value | 0.56 | |
ICASO intracranial major artery stenosis/occlusion, SD standard deviation