Table 2.
Clinical characteristics of 6 non-MMD ICASO patients with the RNF213 p.R4810K variant
| Case | Sex | Age (yrs) | Site of stenosis/occlusion | Hypertension | Diabetes | Hyperlipemia | CHD | Smoking | Drinking |
|---|---|---|---|---|---|---|---|---|---|
| 1 | F | 80 | Occlusion of bilateral anterior inferior cerebellar artery and stenosis of left vertebral artery | 5 years | 2 years | 2 years | 20 years | - | - |
| 2 | F | 52 | Occlusion of the A1 segment of right anterior cerebral artery and stenosis of the left middle cerebral artery | 1 month | - | - | - | - | - |
| 3 | M | 42 | Occlusion of the A1 segment of left anterior cerebral artery | 5 years | 5 years | - | - | - | - |
| 4 | F | 48 | Stenosis of bilateral middle cerebral artery and the right anterior cerebral artery | 8 years | 3 years | - | - | - | - |
| 5 | M | 79 | Occlusion of the left middle cerebral artery | 40 years | 14 years | - | 23 years | - | - |
| 6 | M | 63 | Diffuse stenosis of the M1 segment of the left middle cerebral artery | 25 years | - | - | - | 10 years | - |
ICASO intracranial major artery stenosis/occlusion, MMD moyamoya disease,F female, M male, CHD coronary heart disease