Table 1.
Results of flea infestations at 4 h post-treatment and 4 h after weekly infestations in Study 1
| Day of infestation and flea count | |||||||
|---|---|---|---|---|---|---|---|
| 0 | 7 | 14 | 21 | 28 | 35 | ||
| Control | Arithmetic mean ± SD | 60.9 ± 12.5 | 76.0 ± 9.8 | 78.6 ± 13.1 | 71.0 ± 6.4 | 67.3 ± 5.6 | 73.1 ± 12.3 |
| Geometric mean | 59.9 | 75.4 | 77.7 | 70.8 | 67.1 | 72.3 | |
| Lotilaner | Arithmetic mean ± SD | 26.4 ± 33.8 | 0.1 ± 0.4 | 0.0 ± 0.0 | 1.0 ± 1.3 | 0.8 ± 1.2 | 2.1 ± 1.7 |
| Efficacy (%) | 56.7 | 99.8 | 100.0 | 98.6 | 98.9 | 97.1 | |
| Geometric mean | 6.1 | 0.1 | 0.0 | 0.7 | 0.5 | 1.6 | |
| Efficacy (%) | 89.9 | 99.9 | 100 | 99.0 | 99.3 | 97.8 | |
| Comparison | t (5) = 3.4, P = 0.0194 | t (5) = 55.0, P < 0.0001 | t (5) = 91.5, P < 0.0001 | t (5) = 21.8, P < 0.0001 | t (5) = 18.5, P < 0.0001 | t (5) = 14.9, P < 0.0001 | |
Abbreviation: SD standard deviation