Table 3.
Results of flea infestations at 8 h post-treatment and 8 h after weekly infestations in Study 3
| Day of infestation and flea count | |||||||
|---|---|---|---|---|---|---|---|
| 0 | 7 | 14 | 21 | 28 | 35 | ||
| Control | Arithmetic mean ± SD | 75.1 ± 6.7 | 82.3 ± 7.8 | 80.8 ± 11.4 | 81.4 ± 13.8 | 78.9 ± 13.4 | 76.3 ± 7.4 |
| Geometric mean | 74.9 | 81.9 | 80.0 | 80.4 | 77.9 | 75.9 | |
| Lotilaner | Arithmetic mean ± SD | 0.1 ± 0.4 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.1 ± 0.4 | 0.5 ± 0.8 | 0.4 ± 0.7 |
| Efficacy (%) | 99.8 | 100 | 100 | 99.8 | 99.4 | 99.5 | |
| Geometric mean | 0.1 | 0.0 | 0.0 | 0.1 | 0.4 | 0.3 | |
| Efficacy (%) | 99.9 | 100 | 100 | 99.9 | 99.5 | 99.7 | |
| Comparison | t (5) = 46.0, P < 0.0001 | t (5) = 128.2, P < 0.0001 | t (5) = 40.4, P < 0.0001 | t (5) = 42.1, P < 0.0001 | t (5) = 12.3, P < 0.0001 | t (5) = 27.6, P < 0.0001 | |
Abbreviation: SD standard deviation