Table 5.
Results of flea infestations at 12 h post-treatment and 12 h after weekly infestations in Study 4
| Day of infestation and flea count | |||||||
|---|---|---|---|---|---|---|---|
| 0 | 7 | 14 | 21 | 28 | 35 | ||
| Control | Arithmetic mean ± SD | 89.5 ± 36.9 | 69.8 ± 18.0 | 75.1 ± 22.6 | 75.8 ± 22.6 | 76.5 ± 19.4 | 59.8 ± 10.1 |
| Geometric mean | 83.6 | 67.9 | 72.6 | 73.1 | 74.1 | 59.1 | |
| Lotilaner | Arithmetic mean ± SD | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 | 0.0 ± 0.0 |
| Efficacy (%) | 100 | 100 | 100 | 100 | 100 | 100 | |
| Geometric mean | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | |
| Efficacy (%) | 100 | 100 | 100 | 100 | 100 | 100 | |
| Comparison | t (7) = 32.1, P < 0.0001 | t (7) = 49.7, P < 0.0001 | t (7) = 44.7, P < 0.0001 | t (7) = 43.5, P < 0.0001 | t (7) = 43.9, P < 0.0001 | t (7) = 75.0, P < 0.0001 | |
Abbreviation: SD standard deviation