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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Arch Toxicol. 2017 Mar 17;91(10):3287–3291. doi: 10.1007/s00204-017-1956-3

Table 2.

Urinary concentrations of DEHP and DEHTP metabolites in a convenience sample of U.S. adults

Parent chemical Urinary metabolite Collection year N Select percentilesb (ng/mL) Frequency of detection (%) Geometric Meanb (ng/mL) Median unconjugated metabolitec,d (%)

25th Median 75th 90th
DEHP MEHHP 2016 149 1.8 4.3 10.2 19.0 100 4.1 1.9
2013 92 2.2 4.9 9.4 16.2 100 4.3
2011 81 17 4.2 10.2 22.0 100 4.1
2009 61 2.7 5.1 13.5 21.5 100 5.9
2000 44 4.8 11.2 22.5 30.0 100 8.7
MECPP 2016 149 2.6 6.6 15.3 30.9 100 6.7 45.5
2013 92 4.6 7.9 15.9 29.6 100 7.8
2011 81 4.0 7.3 17.9 41.5 100 9.3
2009 61 5.9 10.9 11.6 32.6 100 10.1
2000 44 6.7 16.6 28.0 37.9 100 12.1
DEHTP MEHHTP 2016 149 1.1 3.0 7.6 22.5 91 3.1 21.2
2013 92 0.6 1.1 3.0 7.1 77 1.3
2011 81 <LODa <LOD 1.1 4.5 44 <LOD
2009 61 <LOD <LOD 0.6 1.8 34 <LOD
2000 44 <LOD <LOD <LOD 1.2 7 <LOD
MECPTP 2016 149 4.5 15.7 37.1 92.2 100 13.1 98.8
2013 92 2.1 4.8 10.8 44.6 95 4.6
2011 81 1.5 2.0 4.8 14.1 86 2.0
2009 61 <LOD <LOD 0.6 1.1 38 <LOD
2000 44 <LOD <LOD <LOD 1.3 18 <LOD
a

LOD-limit of detection; LOD-0.4 ng/mL for both MEHHTP and MECPTP

b

<LOD was treated as LOD√2

c

Only total concentrations >LOD were used in the calculation

d

Only urine samples collected in 2016 were analyzed without β-glucuronidase for unconjugated metabolites