Table 1.

Comparative FASD animal models reporting fetal alcohol-induced cortical phenotypes.

Strain	Animal Model	Dose, intake of EtOH; (v/v)	Period of Exposure	Age of Cortical Analysis	BEC (mg/dL)	Cortical phenotype	Reference
Wistar Rat	IP	20%; 3.5 g/kg/d	E10–18	E18	119–300	Cortical thinning	Aronne et al., 2008
C57 BL6 Mice	SA of EtOH in PMI liquid diet	25%	E7–15	E15	40–120	Cortical thinning	Zhou et al., 2004
CD1 Mice	SA of EtOH in Water	25%; 6.76 ± 0.25 mL/d	E0.5–19.5	P0	103–138	Reduced cortical length	El Shawa et al., 2013
CD1 Mice	SA of EtOH in Water	25%; 6.55 ± 0.2 mL/d	E0.5–19.5	P0, P20, P50	100–135	Thickening of the frontal, somatosensory and visual cortices; thinning of prelimbic and auditory cortex (P0)	Abbott et al., 2016
C57 BL/6 (B6) Mice	SA of EtOH in PMI liquid diet	4%; 13 mL/d	E7–16	E17	120–160	Thinning of the frontal cortex	Current Study

BEC: blood ethanol content; IP: intraperitoneal injection; SA: self-administered.