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. Author manuscript; available in PMC: 2017 Nov 1.
Published in final edited form as: Sci Signal. 2017 Jul 11;10(487):eaam5345. doi: 10.1126/scisignal.aam5345

Fig. 3. Effect of DRG post-microinjection of Cebpb siRNA into the ipsilateral L3/4 DRGs on CCI-induced maintenance of pain hypersensitivity.

Fig. 3

(A to G) Effect of DRG microinjection of Cebpb siRNA, vehicle, or negative control siRNA starting on day 5 after CCI on paw withdrawal frequencies to mechanical stimuli (A and B), paw withdrawal latency to thermal stimulation (C), and paw jumping latency to cold stimulation (D) on the ipsilateral side and on basal paw withdrawal responses to mechanical (E and F) and thermal (G) stimuli on the contralateral side on days 12 and 14 after CCI. n = 10 mice per group. Two-way ANOVA followed by Tukey post hoc test, F2,119 = 26.777 in (A), F2,119 = 31.439 in (B), F2,119 = 15.275 in (C), F2,119 = 18.089 in (D), F2,119 = 0.093 in (E), F2,119 < 0.001 in (F), and F2,119 = 0.157 in (G). **P < 0.01 compared to the vehicle plus CCI group at the corresponding time points.