Table 2.
The association between the expression of FAM83B and clinicopathological features of PDAC in Renji Cohort 2.
| Clinicopathological feature | Total 130 |
Expression of FAM83B | p Value (x2 test) |
|
|---|---|---|---|---|
| High (n=103, 79.2%) |
Low (n=27, 20.8%) |
|||
| Age (years) | ||||
| <65 | 60 | 45 (75.0) | 15 (25.0) | 0.271 |
| ≥65 | 70 | 58 (82.9) | 12 (17.1) | |
| Gender | ||||
| Male | 74 | 60 (81.1) | 14 (18.9) | 0.550 |
| Female | 56 | 43 (76.8) | 13 (23.2) | |
| Tumor size | ||||
| ≤3cm | 48 | 36 (75.0) | 12 (25.0) | 0.363 |
| >3cm | 82 | 67 (81.7) | 15 (18.3) | |
| Clinical stage (AJCC) | ||||
| Stage I / II | 105 | 79 (75.2) | 26 (24.8) | 0.021 |
| Stage III / IV | 25 | 24 (96.0) | 1 (4.0) | |
| T classification | ||||
| T1/T2 | 27 | 20 (74.1) | 7 (25.9) | 0.458 |
| T3/T4 | 103 | 83(80.6) | 20 (19.4) | |
| Lymph node metastasis | ||||
| Absent | 85 | 66 (77.6) | 19 (22.4) | 0.541 |
| Present | 45 | 37 (82.2) | 8 (17.8) | |
| Distant metastasis | ||||
| Absent | 118 | 92 (78.0) | 26 (22.0) | 0.265 |
| Present | 12 | 11 (91.7) | 1 (8.3) | |
| Vascular invasion | ||||
| Absent | 118 | 93 (78.8) | 25 (21.2) | 0.713 |
| Present | 12 | 10 (83.3) | 2 (16.7) | |
| Histological differentiation | ||||
| Well/Moderate | 80 | 63 (78.7) | 17(21.3) | 0.864 |
| Poor | 50 | 40 (80.0) | 10 (20.0) | |
| CA199 level (U/ml) | ||||
| ≤35 | 18 | 16(88.9) | 2 (11.1) | 0.371 |
| >35 | 69 | 55 (79.7) | 14 (20.3) | |
| Missing | 43 | |||
| Vital status | ||||
| Alive | 17 | 9 (52.9) | 8 (47.1) | 0.005 |
| Dead | 95 | 79 (83.2) | 16 (16.8) | |
The bold number represents p<0.05.