Figure 4.

Therapeutic efficacy of combination therapies. Tumor-bearing mice were treated as described in Figure 1. Tumor-bearing mice were randomly assigned to 6 groups, PBS, GD5 i.t., GD5 i.p., DOX i.t., Co i.t., or Co i.p treatment group. After 2 weeks, the volume of the directly treated right tumors (A) and the untreated left tumors (B) were measured. Experimental groups contained at least 5 mice and are representative of at least 2 independent experiments. *p < 0.007, one-way ANOVA, NS, non-significant.