Table 3.
Treatment related toxicities.
| Toxicities | RT alone | Single agent CRT | Double agents' CRT | χ2 | P | |||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Grade 0-1 | ≥ Grade 2 | Grade 0-1 | ≥ Grade 2 | Grade 0-1 | ≥ Grade 2 | |||||||
| Neutropenia | 77(78.6) | 21(21.4) | 53(75.7) | 17(24.3) | 6(37.5) | 10(62.5) | 10.602 | 0.005a | ||||
| Thrombocytopenia | 93(94.9) | 5(5.1) | 62(88.6) | 8(11.4) | 13(81.2) | 3(18.8) | 4.030 | 0.133 | ||||
| Radiation esophagitis | 79(80.6) | 19(19.4) | 59(83.3) | 11(15.7) | 11(68.8) | 5(31.2) | 1.893 | 0.388 | ||||
| Radiation pneumonia | 91(92.9) | 7(7.1) | 67(95.7) | 3(4.3) | 15(93.8) | 1(6.2) | 0.619 | 0.734 | ||||
| Gastrointestinal reaction | 94(95.9) | 4(4.1) | 66(94.3) | 4(5.7) | 6(37.5) | 10(62.5) | 32.605 | <0.001b | ||||
p values less than 0.05 were highlighted in bold.
a: Double agentsvs Single agent CRT, P = 0.003; Double agents' CRT VS RT alone, P = 0.002
b: Double agents VS Single agent CRT, P < 0.001; Double agents' CRT VS RT alone, P< 0.001