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miR-21 inhibitor induces apoptosis and regulates PTEN expression in U266 cells. After transfection, cells were then cultured under normoxia or hypoxia for another 24 hours. (A) Apoptosis rates in each group were examined using flow cytometry. (B) The PTEN protein levels in U266 cells, were detected by the western blot analysis. Data are presented as mean ± SD (n = 3). *P < 0.05 compared to control group.
